1. 首页
  2. 生化科研试剂
  3. 蛋白质组化

Recombinant Human Fibroblast Growth Factor-19

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132687-10 μg 0 ￥3300 请登录
- +
1308132687-50 μg 0 ￥8400 请登录
- +
偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。
别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Fibroblast Growth Factor-19 可以激活一个重要的、胰岛素独立的内分泌通路，调节肝脏蛋白和糖原的代谢。
Synonyms
rHuFGF-19; FGF19 ; 重组人成纤维细胞生长因子-19
Species
Human

Source
E. coli

Accession
O95750

Gene ID
9965

Molecular Weight
Approximately 21.8 kDa

AA Sequence
MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK

Biological Activity
The ED50 is <150 ng/mL as measured by murine Balb/c 3T3 cells, corresponding to a specific activity of >6.7 × 103 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor-19 (rHuFGF-19) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA.

Storage & Stability
Lyophilized recombinant Human Fibroblast Growth Factor-19 (rHuFGF-19) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Fibroblast growth factor 19 (FGF19, also called FGF15 in rodents) is a member of a subfamily of fibroblast growth factors that govern nutrient metabolism. FGF19 binds to a receptor complex composed of the FGF receptor 4 (FGFR4) and a coreceptor called β-Klotho, which are both highly expressed in liver. FGF19 is an enterokine synthesized and released when bile acids are taken up into the ileum. FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis. FGF19 activates a physiologically important, insulin-independent endocrine pathway that regulates hepatic protein and glycogen metabolism[1].
贮存
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
X
QQ