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Recombinant Human Fibroblast Growth Factor-6
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性状 | Recombinant Human Fibroblast Growth Factor-6是成纤维细胞、血管内皮细胞和前列腺癌细胞的一种有丝分裂原。
Synonyms rHuFGF-6; HBGF-6; HST-2; HSTF-2 ; 重组人成纤维细胞生长因子-6 Species Human Source E. coli Accession P10767 Gene ID 2251 Molecular Weight Approximately 18.8 kDa AA Sequence MGTRANNTLL DSRGWGTLLS RSRAGLAGEI AGVNWESGYL VGIKRQRRLY CNVGIGFHLQ VLPDGRISGT HEENPYSLLE ISTVERGVVS LFGVRSALFV AMNSKGRLYA TPSFQEECKF RETLLPNNYN AYESDLYQGT YIALSKYGRV KRGSKVSPIM TVTHFLPRI Biological Activity The ED50 is <2.5 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >4.0 × 105 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor-6 (rHuFGF-6) to 100 μg/mL using ddH2O. Storage & Stability Lyophilized recombinant Human Fibroblast Growth Factor-6 (rHuFGF-6) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Fibroblast growth factor 6 (FGF-6) is a heparin-binding member of the FGF family, which are regulators of cell proliferation, differentiation, and function. FGF-6 binds and signals through the FGF receptors 1c, 2c, and 4[1]. FGF-6 is a potent mitogen for fibroblasts, vascular endothelial cells, and prostate carcinoma cells[2]. |
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