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Recombinant Canine Interleukin-3
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| 性状 | Recombinant Canine Interleukin-3是一种造血生长因子，参与多能造血细胞的存活，增殖和分化。
Synonyms rCaIL-3; Mast cell growth factor; MCGF; Hematopoietic growth factor ; 重组犬白细胞介素-3 Species Canine Source E. coli Accession Q9BDX4 Gene ID 481497 Molecular Weight Approximately 14.0 kDa AA Sequence RPFSTDLPKQ YFTMINEIME MLNKSPSPSE EPLDSNEKET LLEDTLLRPN LDVFLNASSK FHKNGLLIWN NLKEFLPLLP TPTPRGEPIS IMENNWGDFQ RKLKKYLEAL DNFLNFKNKP Biological Activity The ED50 is <0.2 ng/mL as measured by human TF-1 cells, corresponding to a specific activity of >5.0 × 106 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Canine Interleukin-3 (rCaIL-3) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Canine Interleukin-3 (rCaIL-3) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Interleukin-3 (IL-3) is a multipotent hematopoietic growth factor produced by activated T cells, monocytes/macrophages and stroma cells. Addition of IL-3 to the culture medium induces proliferation, maturation and probably self-renewal of pluripotent hematopoietic stem cells and cells of myeloid, erythroid and megakaryocytic lineages[1]. IL-3 preferentially supports the proliferation and differentiation of progenitors at early stages of hematopoietic development. In addition, IL-3 exerts a wide spectrum of biological activities on various target cell populations, including T cells, B cells, eosinophils, basophils and monocytes[2]. |
| 贮存 |
- Recombinant Human Interleukin-19
- Recombinant Mouse Interleukin-19
- Recombinant Human Interleukin-20
- Recombinant Human Interleukin-2 Receptor alpha, His (HEK293-expressed)
- Recombinant Canine Interleukin-3
- Recombinant Human Interleukin-31
- Recombinant Mouse Interleukin-33
- Recombinant Porcine Interleukin-4 (CHO-expressed)
- Recombinant Human Interleukin-4 Receptor (HEK293-expressed)
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