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Recombinant Porcine Interleukin-4 (CHO-expressed)

英文名：
Cas号：
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货号 规格 货期 库存 价格 会员价 订购
1308132732-10 μg 0 ￥3900 请登录
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1308132732-50 μg 0 ￥10400 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Porcine Interleukin-4 (CHO-expressed)是主要的抗炎细胞因子，参与细胞增殖，各种基因表达和避免IL-4表达细胞中的细胞凋亡。
Synonyms
rPoIL-4; BSF-1; IL4 ; 重组猪白细胞介素-4 (CHO表达)
Species
Porcine

Source
CHO

Accession
Q04745

Gene ID
397225

Molecular Weight
Approximately 15 kDa

AA Sequence
HKCDITLQEI IKTLNILTAR KNSCMELPVT DVFAAPENTT EKETFCRAST VLRHIYRHHT CMKSLLSGLD RNLSSMANMT CSVHEAKKST LKDFLERLKT IMKEKYSKC

Biological Activity
The ED50 is <0.25 ng/mL as measured by TF-1 human erythroleukemic cells, corresponding to a specific activity of >4.0 × 106 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Porcine Interleukin-4 (CHO-expressed) (rPoIL-4) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Porcine Interleukin-4 (CHO-expressed) (rPoIL-4) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
The effect of IL-4 signaling is mediated through the IL-4 receptor alpha chain (IL-4Rα). Upon binding to its ligand, IL-4Rα dimerizes either with the common gamma chain (γc) to produce the type-1 signaling complex located mainly on hematopoietic cells, or with the IL-13 receptor alpha 1 (IL-13Rα1) to produce the type-2 complex, which is expressed also on non-hematopoietic cells[1].
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