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Recombinant Mouse MEC/CCL28
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性状 | Recombinant Mouse MEC/CCL28 是一种 CC 趋化因子,通过将免疫细胞招募到特定位置,在粘膜免疫系统的分离和区划中起关键作用。
Synonyms rMuMEC/CCL28; C-C motif chemokine 28; SCYA28 ; 重组小鼠 MEC/CCL28 Species Mouse Source E. coli Accession Q9JIL2 Gene ID 56838 Molecular Weight Approximately 12.6 kDa AA Sequence SEAILPMASS CCTEVSHHVS GRLLERVSSC SIQRADGDCD LAAVILHVKR RRICISPHNR TLKQWMRASE VKKNGRENVC SGKKQPSRKD RKGHTTRKHR TRGTHRHEAS R Biological Activity Full biological activity determined by a chemotaxis bioassay using murine lymphocytes is in a concentration range of 1.0-10.0 ng/ml. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 150 mM NaCl. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse MEC/CCL28 (rMuMEC/CCL28) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Mouse MEC/CCL28 (rMuMEC/CCL28) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Mouse MEC/CCL28 is a CC chemokine primarily expressed in thymic dendritic cells and mucosal epithelial cells, and plays a key role in the segregation and the compartmentalization of the mucosal immune system through recruitment of immune cells to specific locations. CCL28 also called mucosae-associated epithelial chemokine (MEC), is expressed in most human, mouse and pig mucosal tissues including the salivary gland, mammary gland (MG), small and large intestines and trachea, where it appears to be predominantly produced by epithelial cells[1]. |
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