Recombinant Human MIP-1 beta/CCL4

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Cas号:
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1308132766-50 μg 0 ¥8400 请登录
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产品参数
性状 Recombinant Human MIP-1 beta/CCL4 是一种促趋化因子,既能够在各种炎症条件下促进白细胞聚集,又有助于对人类免疫缺陷 1 型病毒产生免疫保护
Synonyms
rHuMIP-1β/CCL4; C-C motif chemokine 4; LAG-1; Macrophage inflammatory protein 1-beta; SCYA4 ; 重组人 MIP-1 beta/CCL4
Species
Human

Source
E. coli

Accession
P13236

Gene ID
6351

Molecular Weight
Approximately 7.6 kDa

AA Sequence
APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN

Biological Activity
The ED50 is <100 ng/mL as measured by CHO-K1/Gα15/hCCR5 cells (human Gα15 and human CCR5 stably expressed in CHO-K1 cells).

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human MIP-1 beta/CCL4 (rHuMIP-1β/CCL4) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human MIP-1 beta/CCL4 (rHuMIP-1β/CCL4) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Human macrophage inflammatory protein-1 (MIP-1β) 1 is a proinflammatory chemokine that both promotes leukocyte accumulation in various inflammatory conditions and contributes to protective immunity against human immunodeficiency virus type 1 (HIV-1) (1-5)[1].
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