Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20

英文名:
Cas号:
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1308132771-10 μg 0 ¥3900 请登录
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1308132771-50 μg 0 ¥13900 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 是一种 CC 趋化因子配体,受体为 CCR6。
Synonyms
rMuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20 ; 重组小鼠巨噬细胞炎性蛋白-3 alpha/CCL20
Species
Mouse

Source
E. coli

Accession
O89093

Gene ID
20297

Molecular Weight
Approximately 8.0 kDa

AA Sequence
ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM

Biological Activity
Full biological activity determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/ml.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 (rMuMIP-3α/CCL20) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA.

Storage & Stability
Lyophilized recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 (rMuMIP-3α/CCL20) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
CCL20 is a C-C motif chemokine ligand, which has C-C motif Chemokine Receptor 6 (CCR6) as its sole receptor and tissues producing CCL20 recruit CCR6 expressing immune cells[1]. The CCL20/CCR6 axis is also involved in various autoimmune diseases and in other cancers besides HCC[2].
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