Recombinant Human MIP-3 alpha/CCL20

英文名:
Cas号:
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1308132770-50 μg 0 ¥8400 请登录
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别 名
Cas号
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分子式
分子量
产品参数
性状 Recombinant Human MIP-3 alpha/CCL20 是一种 CC 趋化因子配体,受体为 CCR6。
Synonyms
rHuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20 ; 重组人 MIP-3 alpha/CCL20
Species
Human

Source
E. coli

Accession
P78556

Gene ID
6364

Molecular Weight
Approximately 8.0 kDa

AA Sequence
ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM

Biological Activity
The ED50 is <200 ng/mL as measured by CHO-K1/Gα15/hCXCR6 cells (human Gα15 and human CXCR6 stably expressed in CHO-K1 cells).

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against 53mM Na2HPO4, 147 mM NaH2PO4, 300 mM NaCl, pH 6.5.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human MIP-3 alpha/CCL20 (rHuMIP-3α/CCL20) to 100 µg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human MIP-3 alpha/CCL20 (rHuMIP-3α/CCL20) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
CCL20 is a C-C motif chemokine ligand, which has C-C motif Chemokine Receptor 6 (CCR6) as its sole receptor and tissues producing CCL20 recruit CCR6 expressing immune cells[1]. The CCL20/CCR6 axis is also involved in various autoimmune diseases and in other cancers besides HCC[2].
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