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Recombinant Human MIP-3 alpha/CCL20 (CHO-expressed)
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性状 | Recombinant Human MIP-3 alpha/CCL20 (CHO-expressed) 是一种 CC 趋化因子配体,受体为 CCR6。
Synonyms rHuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20 ; 重组人 MIP-3 alpha/CCL20 (CHO 细胞表达) Species Human Source CHO Accession P78556 Gene ID 6364 Molecular Weight Approximately 8 kDa AA Sequence ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM Biological Activity The ED50 is <200 ng/mL as measured by CHO-K1/Gα15/hCCR6 cells (human Gα15 and human CCR6 stably expressed in CHO-K1 cells). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human MIP-3 alpha/CCL20 (CHO-expressed) (rHuMIP-3α/CCL20) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human MIP-3 alpha/CCL20 (CHO-expressed) (rHuMIP-3α/CCL20) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CCL20 is a C-C motif chemokine ligand, which has C-C motif Chemokine Receptor 6 (CCR6) as its sole receptor and tissues producing CCL20 recruit CCR6 expressing immune cells[1]. The CCL20/CCR6 axis is also involved in various autoimmune diseases and in other cancers besides HCC[2]. |
贮存 |
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