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Recombinant Human TECK/CCL25
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性状 | Recombinant Human TECK/CCL25 参与T细胞的发育和细胞迁移小肠的过程。
Synonyms rHuTECK/CCL25; C-C motif chemokine 25; SCYA25 ; 重组人 CC 趋化因子25 Species Human Source E. coli Accession O15444 Gene ID 6370 Molecular Weight Approximately 14.3 kDa AA Sequence MQGVFEDCCL AYHYPIGWAV LRRAWTYRIQ EVSGSCNLPA AIFYLPKRHR KVCGNPKSRE VQRAMKLLDA RNKVFAKLHH NTQTFQAGPH AVKKLSSGNS KLSSSKFSNP ISSSKRNVSL LISANSGL Biological Activity Full biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1.0-10 ng/ml. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 150 mM NaCl. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human TECK/CCL25 (rHuTECK/CCL25) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Human TECK/CCL25 (rHuTECK/CCL25) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Thymus-expressed chemokine (TECK) or CCL25, a CC chemokine expressed predominantly in thymus and epithelium of the small intestine and a ligand of CCR9, mediates chemotaxis of CCR9-bearing T cells. CCL25 is the predominant chemokine involved in cellular migration to the small intestine[1]. CCL25 mediates the localization of recently activated CD8αβ+ lymphocytes to the small-intestinal mucosa[2]. |
贮存 |
- Recombinant Mouse Sonic Hedgehog (CHO-expressed)
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- Recombinant Human TECK/CCL25
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