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Recombinant Human Transforming Growth Factor alpha (CHO-expressed)

英文名：
Cas号：
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货号 规格 货期 库存 价格 会员价 订购
1308132804-10 μg 0 ￥1400 请登录
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1308132804-50 μg 0 ￥3200 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Transforming Growth Factor alpha (CHO-expressed) 是一种有效的血管生成介质和有丝分裂多肽。
Synonyms
rHuTGF-α; ETGF; TGFA ; 重组人转化生长因子 (CHO细胞表达)
Species
Human

Source
CHO

Accession
P01135

Gene ID
7039

Molecular Weight
8-10 kDa

AA Sequence
VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA

Biological Activity
The ED50 is <0.4 ng/mL as measured by 3T3 cells.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Transforming Growth Factor alpha (CHO-expressed) (rHuTGF-α) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human Transforming Growth Factor alpha (CHO-expressed) (rHuTGF-α) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Transforming growth factors (TGF's) are polypeptides that can confer phenotypic transformation to several normal cells. TGF-α binds to the receptor for epidermal growth factor (EGF) and has been isolated from a variety of tumor cells. TGF-α is synthesized in embryos during early fetal development, in several virally transformed cells, and in a large variety of human tumors[1]. TGF-α is a member of the epidermal growth factor family of mitogens and associated with progression of transformed properties in human colon cancer cells[2].
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