Recombinant Human Fibroblast Growth Factor 8

英文名:
Cas号:
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分子式
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产品参数
性状 Recombinant Human Fibroblast Growth Factor 8 是胚胎发育过程中的一个重要因子,参与前列腺癌的进展。
Synonyms
rHuFGF-8; FGF-8; AIGF; HBGF-8 ; 重组人成纤维细胞生长因子 8
Species
Human

Source
E. coli

Accession
P55075

Gene ID
2253

Molecular Weight
Approximately 22.5 kDa

AA Sequence
MQVTVQSSPN FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA PEPR

Biological Activity
The ED50 is <5 ng/mL as measured by TF-1 cells, corresponding to a specific activity of >2 × 105 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor 8 (rHuFGF-8) to 100 µg/mL using ddH2O.

Storage & Stability
Lyophilized recombinant Human Fibroblast Growth Factor 8 (rHuFGF-8) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Fibroblast Growth Factor 8 is an essential factor during embryonic development, overexpressed in several tumor types. Fibroblast Growth Factor 8 stimulates anti-apoptotic pathways and prevents tumor cell death[1].
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