Recombinant Mouse Interleukin-17A (CHO-expressed)

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Cas号:
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分子式
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产品参数
性状 Recombinant Mouse Interleukin-17A (CHO-expressed) 是一种细胞因子,在先天免疫和后天免疫中发挥重要作用。
Synonyms
rMuIL-17A; CTLA-8; IL-17A ; 重组小鼠白介素-17A (CHO 细胞表达)
Species
Mouse

Source
CHO

Accession
Q62386

Gene ID
16171

Molecular Weight
15-22 kDa

AA Sequence
AAIIPQSSAC PNTEAKDFLQ NVKVNLKVFN SLGAKVSSRR PSDYLNRSTS PWTLHRNEDP DRYPSVIWEA QCRHQRCVNA EGKLDHHMNS VLIQQEILVL KREPESCPFT FRVEKMLVGV GCTCVASIVR QAA

Biological Activity
Full biological activity determined by its ability to induce IL-1a, IL-4 and IL-6 production by primary mouse splenocytes.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Mouse Interleukin-17A (CHO-expressed) (rMuIL-17A) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Mouse Interleukin-17A (CHO-expressed) (rMuIL-17A) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
IL-17A plays important roles in both innate and acquired immunity and is, especially, involved in the accumulation of polymorphonuclear neutrophil leukocytes. IL-17A mediates crucial crosstalk between the immune system and various epithelial tissues, initiating a series of defensive mechanisms against bacterial and fungal infections[1].
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