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Recombinant Mouse Interleukin-6, His (CHO-expressed)
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| 性状 | Recombinant Mouse Interleukin-6, His (CHO-expressed) 是带有 His 标签的 白细胞介素6， 是具有多功能的细胞因子，可调节多种免疫和炎症反应。
Synonyms rMuIL-6, His; B cell differentiation factor; IL6 ; 重组小鼠白细胞介素- 6, His (CHO 表达) Species Mouse Source CHO Accession P08505 Gene ID 16193 Molecular Weight 24-26 kDa AA Sequence FPTSQVRRGD FTEDTTPNRP VYTTSQVGGL ITHVLWEIVE MRKELCNGNS DCMNNDDALA ENNLKLPEIQ RNDGCYQTGY NQEICLLKIS SGLLEYHSYL EYMKNNLKDN KKDKARVLQR DTETLIHIFN QEVKDLHKIV LPTPISNALL TDKLESQKEW LRTKTIQFIL KSLEEFLKVT LRSTRQTHHH HHH Biological Activity The ED50 is <3 pg/mL as measured by 7TD1 cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse Interleukin-6, His (CHO-expressed) (rMuIL-6, His) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Mouse Interleukin-6, His (CHO-expressed) (rMuIL-6, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Interleukin-6 (IL-6) is one of the most important mediators of the acute phase reaction in liver[1]. Interleukin 6 (IL-6), promptly and transiently produced in response to infections and tissue injuries, contributes to host defense through the stimulation of acute phase responses, hematopoiesis, and immune reactions. IL-6 promotes specific differentiation of naïve CD4+ T cells, thus performing an important function in the linking of innate to acquired immune response. IL-6, in combination with transforming growth factor (TGF)-β, is indispensable for Th17 differentiation from naïve CD4+ T cells, but that IL-6 also inhibits TGF-β-induced Treg differentiation[1]. |
| 贮存 |
- Recombinant Human Interleukin-2 Receptor alpha/CD25, Fc Chimera (HEK293-expressed)
- Recombinant Rat Interleukin-3, His (CHO-expressed)
- Recombinant Rat Interleukin-3 beta
- Recombinant Human Interleukin-6 Receptor alpha (Sf9 insect cells-expressed)
- Recombinant Mouse Interleukin-6, His (CHO-expressed)
- Recombinant Human Interleukin-8/CXCL8 (CHO-expressed)
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