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Recombinant Human Macrophage Inflammatory Protein-1 beta/CCL4 (CHO-expressed)
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性状 | Recombinant Human Macrophage Inflammatory Protein-1 beta/CCL4 (CHO-expressed) 是一种促趋化因子,既能够在各种炎症条件下促进白细胞聚集,又有助于对人类免疫缺陷 1 型病毒产生免疫保护。
Synonyms rHuMIP-1β/CCL4; MIP-1β; C-C motif chemokine 4; ACT-2; SCYA4 ; 重组人巨噬细胞炎症蛋白-1 β/CCL4 (CHO 表达) Species Human Source CHO Accession P13236 Gene ID 388372 Molecular Weight 10-19 kDa AA Sequence APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRSKQV CADPSESWVQ EYVYDLELN Biological Activity The EC50 is <150 ng/mL as measured on Ca2+ mobilization assay in CHO-K1/Gα15/hCCR5 cells (human Gα15 and human CCR5 stably expressed in CHO-K1 cells). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Macrophage Inflammatory Protein-1 beta/CCL4 (CHO-expressed) (rHuMIP-1β/CCL4) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Macrophage Inflammatory Protein-1 beta/CCL4 (CHO-expressed) (rHuMIP-1β/CCL4) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Macrophage inflammatory protein-1 (MIP-1β) 1 is a proinflammatory chemokine that both promotes leukocyte accumulation in various inflammatory conditions and contributes to protective immunity against human immunodeficiency virus type 1 (HIV-1) (1-5)[1]. |
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- Recombinant Human Macrophage Inflammatory Protein-1 beta/CCL4 (CHO-expressed)
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