Recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed)

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Cas号:
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分子式
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产品参数
性状 Recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) 是一种 CC 趋化因子,能够通过 CCR1 诱导内皮细胞的迁移和管系形成。
Synonyms
rHuMPIF/CCL23, 85a.a.; C-C motif chemokine 23; SCYA23; MPIF-1; Ck-beta8; MIP-3 ; 重组人MPIF/CCL23,85a.a (CHO 表达)
Species
Human

Source
CHO

Accession
P55773

Gene ID
6368

Molecular Weight
Approximately 11.3 kDa

AA Sequence
RFHATSADCC ISYTPRSIPC SLLESYFETN SECSKPGVIF LTKKGRRFCA NPSDKQVQVC VRMLKLDTRI KTRKN

Biological Activity
The EC50 is <1 μg/mL as measured on Ca2+ mobilization assay in CHO-K1/Gα15/hCCR1 cells (human Gα15 and human CCR5 stably expressed in CHO-K1 cells).

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) (rHuMPIF/CCL23, 85a.a.) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) (rHuMPIF/CCL23, 85a.a.) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Human CCL23 (also known as CKb8, MPIF-1, or MIP-3) is a CC chemokine, which induces endothelial cell migration and tube formation via CCR1. CCL23 also exhibits chemotactic activity on monocytes and dendritic cells, and inhibits the formation of bone marrow-derived colony-forming cells[1].
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