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Recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed)
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性状 | Recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) 是一种 CC 趋化因子,能够通过 CCR1 诱导内皮细胞的迁移和管系形成。
Synonyms rHuMPIF/CCL23, 85a.a.; C-C motif chemokine 23; SCYA23; MPIF-1; Ck-beta8; MIP-3 ; 重组人MPIF/CCL23,85a.a (CHO 表达) Species Human Source CHO Accession P55773 Gene ID 6368 Molecular Weight Approximately 11.3 kDa AA Sequence RFHATSADCC ISYTPRSIPC SLLESYFETN SECSKPGVIF LTKKGRRFCA NPSDKQVQVC VRMLKLDTRI KTRKN Biological Activity The EC50 is <1 μg/mL as measured on Ca2+ mobilization assay in CHO-K1/Gα15/hCCR1 cells (human Gα15 and human CCR5 stably expressed in CHO-K1 cells). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) (rHuMPIF/CCL23, 85a.a.) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human MPIF/CCL23, 85a.a. (CHO-expressed) (rHuMPIF/CCL23, 85a.a.) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Human CCL23 (also known as CKb8, MPIF-1, or MIP-3) is a CC chemokine, which induces endothelial cell migration and tube formation via CCR1. CCL23 also exhibits chemotactic activity on monocytes and dendritic cells, and inhibits the formation of bone marrow-derived colony-forming cells[1]. |
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