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Recombinant Human NANOG-TAT

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132907-10 μg 0 ￥3200 请登录
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1308132907-50 μg 0 ￥8400 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human NANOG-TAT是一种多域同源框转录因子，具有维持多能干细胞未分化状态的功能。
Synonyms
rHuNANOG-TAT; Homeobox protein NANOG ; 重组人NANOG-TAT
Species
Human

Source
E. coli

Accession
Q9H9S0

Gene ID
79923

Molecular Weight
Approximately 36.2 kDa

AA Sequence
MSVDPACPQS LPCFEASDCK ESSPMPVICG PEENYPSLQM SSAEMPHTET VSPLPSSMDL LIQDSPDSST SPKGKQPTSA ENSVAKKEDK VPVKKQKTRT VFSSTQLCVL NDRFQRQKYL SLQQMQELSN ILNLSYKQVK TWFQNQRMKS KRWQKNNWPK NSNGVTQKAS APTYPSLYSS YHQGCLVNPT GNLPMWSNQT WNNSTWSNQT QNIQSWSNHS WNTQTWCTQS WNNQAWNSPF YNCGEESLQS CMQFQPNSPA SDLEAALEAA GEGLNVIQQT TRYFSTPQTM DLFLNYSMNM QPEDVGGYGR KKRRQRRR

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against 10 mM PB, 300 mM NaCl, pH 7.4.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human NANOG-TAT (rHuNANOG-TAT) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Human NANOG-TAT (rHuNANOG-TAT) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53[1].
贮存
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