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AGR2 DyLight® 488

英文名：Rabbit Monoclonal Antibody
Cas号：
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别 名 AGR2 antibody, AG2 antibody, GOB-4 antibody, HAG-2 antibody, PDIA17 antibody, XAG-2 antibody, Anterior gradient protein 2 homolog antibody, HPC8 antibody, Secreted cement gland protein XAG-2 homolog antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】The anterior gradient protein-2 (AGR2) is
a cancer cell marker specifically up-regulated in
response to depletion of serum and oxygen. It has
been identified as a tumor marker in primary and
secondary cancer lesions, and as a marker for detection
of circulating tumor cells. Elevated levels of AGR2
are known to increase the metastatic potential of
cancer cells (1). Specifically, AGR2 may serve as a
useful molecular marker and/or potential therapeutic
target for hormone-responsive breast tumours (2).
AGR2 expression promotes tumor growth in
esophageal adenocarcinoma cells as well. Expression
was detected in proliferating and differentiated
intestinal cells of secretory lineage, suggesting that
AGR2 may be important for the growth and development of
the intestine as well as esophageal adenocarcinomas (3).


Recommended Applications

ICC, FC
Applications and Recommended Dilution Factors

ICC: 1:100
FC: 1:100
Species Reactivity

Human

Products Data
Immunofluorescent analysis of HeLa cells using AGR2
RabMAb (DyLight® 488 conjugate, cat.# 4568-1) (green)
and dapi (blue).
Flow cytometric analysis of Hela cells using AGR2
RabMAb (DyLight® 488 conjugate, cat.# 4568-1) (red)
compared to a nonspecific negative control antibody (green).

Specificity

A synthetic peptide corresponding to residues in human
AGR2 was used as an immunogen.
性状 【反应特异性】Human
【克隆 ID】EPR3278
【用途】ICC , FC
【抗原分子量】17kDa
贮存 Storage Condition and Buffer Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt.
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