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AIF Rabbit Antibody
英文名:Rabbit Monoclonal IgG
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113315-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | Programmed cell death protein 8 |
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产品参数 | 【产品介绍】AIF, o r apoptosis-inducing fact o r , is
a flavoprotein localized to the mitochondrial membrane that plays a primary role in caspase-independent cell death, o r apoptosis (1,2). AIF translocates to the nucleus when apoptosis is induced a n d causes mitochondria to release the apoptogenic proteins, cytochrome c a n d caspase-9. Apoptotic activity of AIF leads to chromatin condensation a n d DNA fragmentation (1). Similar to cytochrome c, AIF is a bifunctional protein with an oxid o r eductase function a n d a second apoptogenic function. In contrast to cytochrome c, however, AIF acts in a caspase-independent fashion (2,3,4). WB: 1:1,000 IHC: 1:500 ICC: 1:500 Flow Cytometry: 1:50 IP: 1:10 A. Western blot analysis of K562 cell lysate using anti-AIF RabMAb (catalog #1020-1), 1:1,000 dilution. B. Immunohistochemical analysis of paraffin-embedded human cervical carcinoma using anti-AIF RabMAb (catalog #1020-1). C. Immunoflu o r escent staining of HeLa cells, using AIF RabMAb. (Green flu o r escence- AIF localized in mitochondria, Red - PI nuclear staining). (catalog #1020-1). D. Flow cytometric analysis of permeabilized K562 cells using anti-AIF RabMAb (red) (catalog #1020-1) o r a rabbit IgG (negative)(green). |
性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】E20 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】67 kDa |
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