Akt1 Phospho (pS129) (AKT1)

英文名:Rabbit Monoclonal Antibody
Cas号:
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别 名 AKT1 antibody, AKT antibody, MGC99656 antibody, PKB antibody, PKB-ALPHA antibody, PRKBA antibody, RAC antibody, RAC-ALPHA antibody, RAC-alpha serine/threonine-protein kinase antibody, Proto-oncogene c-Akt antibody, RAC-PK-alpha antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Akt1/PKBa is a Serine/Threonine protein
kinase whose kinase activity plays a key role in
various cellular functions, including apoptosis,
glycogen synthesis, and cell growth. Akt1/PKBa is
activated by various growth and survival
factors (1). Akt1/PKBa inhibits apoptosis by
phosphorylating and inactivating several targets,
including caspase-9 (2). Akt1/PKBa regulates
glycogen synthesis by phosphorylating and
inactivating glycogen synthase kinase-3a and b (3,4).


Recommended Applications

WB
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data
Western blot analysis on MCF-7 cell lysates using
anti-Akt1 Phospho (pS129) RabMAb (cat. #5508-1).
Cells were either (A) untreated or (B) treated
with Alkaline Phosphatase.

Specificity

A phospho specific peptide corresponding to
residues surrounding Serine 129 of human Akt1 was used as
an immunogen. This antibody only detects
Akt1 phosphorylated at Serine 129.
性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6150
【用途】WB
【抗原分子量】60kDa
贮存 Storage Condition and Buffer Store at -20° C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt.
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