APP Phospho (pT743)

英文名:Rabbit Monoclonal Antibody
Cas号:
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货号 规格 货期 库存 价格 会员价 订购
1308113338-100ul  现货 0 ¥0 请登录
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别 名 APP antibody, AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN2 antibody, C31 antibody, Gamma-CTF(50) antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Alzheimer's disease (AD) is characterized by
the presence of senile plaques in the brain and blood
vessel walls. Amyloid Beta A4 (Aβ4) protein has been
found to be the principal constituent of senile plaques
of ADs patients (1-2). APP is proteolytically cleaved
to generate the 4 kDa Aβ4 protein. Two variants of Aβ4
can be detected; Aβ1-40 short-tailed and Aβ1-42 long-tailed (3-4).


Recommended Applications

WB, IP
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
IP: 1:10 - 100
Species Reactivity *

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis

Products Data

Western blot analysis on human brain lysates
using anti-Phospho-APP (pT743) RabMAb (cat. #3926-1).
Cells were either (A) untreated (B) treated with
Lambda Phosphatase.

Specificity

A phospho specific peptide corresponding to
residues surrounding Threonine 743 of human APP was used
as an immunogen. This antibody only detects
APP phosphorylated at Threonine 743.

性状 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR826(2)
【用途】WB , IP
【抗原分子量】100 - 120kDa
贮存 Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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