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Apolipoprotein E (N-term) (APOE)
英文名:Rabbit Monoclonal Antibody
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308113336-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | APOE antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, MGC1571 antibody, Apolipoprotein E antibody, antibody |
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产品参数 | 【产品介绍】The apolipoproteins are family of
amphipathic lipoproteins that plays a crucial role in lipid metabolism. In particular, apolipoprotein E (apo E) is a major component of high density lipoproteins (HDL) chylomicrons and very low-density lipoprotein (VLDL), which functions to remove excess cholesterol. Apo E mediates lipid metabolism and cholesterol homeostasis by binding to several hepatic lipoprotein receptors, such as low density lipoprotein receptor (LDLR) and the LDLR-related protein (1). Apo E deficiency is linked to hyperlipoproteinemia type III; a genetic disorder characterized by elevated plasma cholesterol and triglyceride levels and accelerated coronary artery disease (2). Three major isoforms of Apo E (E2, E3, E4) has been identified, with E3 being the most common in human. E4 presence has been associated to increase probability of developing late-onset form of Alzheimer disease (3). Recommended Applications WB, IHC, IP, FC Applications and Recommended Dilution Factors WB: 1:500 - 1000 IHC: 1:100 - 1:250 IP: 1:70 FC: 1:30 Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on human serum using anti-Apo E RabMAb. (Cat. # 1981-1). B. Immunohistochemical analysis of paraffin-embedded human fetal liver using anti-Apo E RabMAb (cat. # 1981-1). Specificity A synthetic peptide corresponding to residues near the N-term of human apolipoprotein E was used as an immunogen. |
性状 | 【反应特异性】Human
【克隆 ID】EP1373Y 【用途】WB , IHC , FC , IP 【抗原分子量】36kDa |
贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |