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Ape 1 (APEX1)
英文名：Rabbit Monoclonal Antibody
Cas号：
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113334-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | APEX1 antibody, APE antibody, APE1 antibody, APEN antibody, APEX antibody, APX antibody, HAP1 antibody, REF1 antibody, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial antibody, REF-1 antibody, Redox factor-1 antibody |
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| 产品参数 | 【产品介绍】Apurinic endonuclease (Ape 1) functions as
a major DNA repair enzyme that is essential for embryogenesis and cell viability (1). It is involved in the base excision repair (BER) pathway and acts as a reduction-oxidation signaling factor to maintain transcription factors in an active reduced state (2). Ape 1 plays a critical role as a transcriptional coactivator for different transcription factors (i.e. AP-1, NF-kappaB, p53) in controlling different cellular processes such as apoptosis, proliferation, and differentiation (3). Elevated levels of Ape 1 have been found in cancers such as ovarian, cervical, and prostate (4). Recommended Applications WB, IHC Applications and Recommended Dilution Factors WB: 1:10,000-50,000 IHC: 1 : 100 - 250 Species Reactivity * Human, Mouse, Rat *Mouse cross reactivity tested by western blot and IHC Rat cross reactivity tested by western blot only Products Data Western blot analysis on (A) K562, (B) HepG2, and (C) Raji cell lysates using anti-Ape 1 RabMAb (cat. #2851-1). Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Ape 1 RabMAb (cat. #2851-1). Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Ape 1RabMAb (cat. #2851-1). Specificity A synthetic peptide corresponding to residues near the N-terminus in human Ape 1 was used as an immunogen. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR4022 【用途】WB , IHC 【抗原分子量】36kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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