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Apolipoprotein A-II (ApoA-II) (APOA2)

英文名：Rabbit Monoclonal Antibody
Cas号：
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别 名 APOA2 antibody, Apo-AII antibody, ApoA-II antibody, apoAII antibody, Apolipoprotein A-II(1-76) antibody, Apolipoprotein A2 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Apolipoprotein A II is the second most
abundant protein of the high density lipoprotein
particles, accounting for 20% of protein mass of HDL.
The concentration of ApoA-I and ApoA-II is
inversely correlated with the frequency of heart disease
in human (1). In studies with mice and humans,
ApoA-II levels have been associated with
increased susceptibility to atherosclerosis, increased
free fatty acid levels, increased body fat, and
increased insulin resistance (2). ApoA-II consists of
three potential amphipathic helices of 17 residues
each, which contribute to the lipid-binding properties
of this apolipoprotein (3). Currently, the
best characterized activity of apoA-II is its
potent antagonism of the anti-atherogenic
and anti-inflammatory activities of ApoA-I, probably due
to its competition with the latter for lipid acyl
side chains of HDL (1).


Recommended Applications

WB, ICC, FC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 5,000
ICC: 1:100 - 250
FC: 1:50
Species Reactivity

Human

Products Data
Western blot analysis on human plasma lysates
using anti-Apolipoprotein A-II (ApoA-II) RabMAb
(cat. #2744-1).

Immunofluorescent staining of HEPG2 cells using
anti-ApoAII RabMAb (cat. #2744-1).

Specificity

A synthetic peptide corresponding to residues in
human Apolipoprotein A-II (ApoA-II) was used as an immunogen.
性状 【反应特异性】Human
【克隆 ID】EPR2913
【用途】WB , ICC , FC
【抗原分子量】11kDa
贮存 Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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