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Bak Rabbit Antibody
英文名：Rabbit Monoclonal IgG
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113356-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | Apoptosis regulat o r BAK, Bcl-2-like 7 protein |
| Cas号 | |
| M D L | |
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| 产品参数 | 【产品介绍】Bak a pro-apoptotic analog to Bax, is a
member of the Bcl-2 family of proteins. During mitochondria-regulated programmed cell death, Bak promotes apoptosis by binding Bcl-2 a n d inhibiting its anti-apoptotic function (1). Upon apoptotic stimulation, Bak translocates from the cytosol to the mitochondrial membrane (2). Pro-apoptotic cascade activates BID, which oligomerizes Bak into p o r es that result in the release of cytochrome c (2, 3). In healthy cells, Bak associate with Bcl-xL a n d Mcl-1 but not with Bcl-2, Bcl-w o r A1 a n d only when freed of both Bak will induce apoptosis. WB: 1:1,000-5,000 IHC: 1:250-500 ICC: 1:250-500 Flow Cytometry: 1:10 A. Western blot analysis on Hela cell lysate using anti-Bak RabMAb (cat. # 1542-1). dilution 1:5,000. B. Immunohistochemical analysis of paraffin-embedded human stomack carcinoma using anti-Bak RabMAb (cat. # 1542-1). |
| 性状 | 【反应特异性】Human
【克隆 ID】Y164 【用途】WB , IHC , ICC , FC 【抗原分子量】23 kDa |
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