|
|
|
| 生化试剂 >> 抗体产品 >> 一抗 |
| |
B-Raf Phospho (pT401)
Rabbit Monoclonal IgG |
| 别 名： |
p94, v-Raf murine sarcoma viral oncogene homolog B1 |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177578 |
B-Raf Phospho (pT401) |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR2208Y
【用途】WB , IP
【抗原分子量】94 kDa |
| 质量标准： |
【产品介绍】B-Raf, also know as c-Rmil, is
a Serine/Threonine protein kinase member of the Raf
family which includes Raf-1 a n d A-Raf. B-Raf is
involved in the transduction of mitogenic signals from
the cell membrane to the nucleus (1). Composed of
three conserved region (CR1, CR2, CR3) B-Raf is
expressed primarily in the brain a n d in the nervous
system (2). It has been observed that MAPK is activated
by B-Raf in response to nerve growth fact o r (3).
M o r e than 60% of malignant melanomas were found
to contain a specific mutation, B-Raf (V599E) the product
of which possesses constitutive kinase activity
(4). Mutations in B-Raf have also been identified in
lung cancer a n d non-Hodgkin lymphoma.
WB: 1:1000 - 5000
ICC: 1:100 – 250
IP: 1:20
A. Western blot analysis on PC-12 cell lysates
using anti-Phospho-B-Raf (p401) RabMAb
(cat. #2298-1), 1:5000 dilution. Cells were
either (A) untreated (B) treated with TPA. |
|
沪公网安备 31012002003054号
