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B-Raf Phospho (pT401)
英文名：Rabbit Monoclonal IgG
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113377-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | p94, v-Raf murine sarcoma viral oncogene homolog B1 |
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| 产品参数 | 【产品介绍】B-Raf, also know as c-Rmil, is
a Serine/Threonine protein kinase member of the Raf family which includes Raf-1 a n d A-Raf. B-Raf is involved in the transduction of mitogenic signals from the cell membrane to the nucleus (1). Composed of three conserved region (CR1, CR2, CR3) B-Raf is expressed primarily in the brain a n d in the nervous system (2). It has been observed that MAPK is activated by B-Raf in response to nerve growth fact o r (3). M o r e than 60% of malignant melanomas were found to contain a specific mutation, B-Raf (V599E) the product of which possesses constitutive kinase activity (4). Mutations in B-Raf have also been identified in lung cancer a n d non-Hodgkin lymphoma. WB: 1:1000 - 5000 ICC: 1:100 – 250 IP: 1:20 A. Western blot analysis on PC-12 cell lysates using anti-Phospho-B-Raf (p401) RabMAb (cat. #2298-1), 1:5000 dilution. Cells were either (A) untreated (B) treated with TPA. |
| 性状 | 【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR2208Y 【用途】WB , IP 【抗原分子量】94 kDa |
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