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Cripto 1 / 3 (TDGF1)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113465-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | TDGF1 antibody, CR antibody, CRGF antibody, CRIPTO antibody, Teratocarcinoma-derived growth factor 1 antibody, Epidermal growth factor-like cripto protein CR1 antibody |
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| 产品参数 | 【产品介绍】Cripto 1, also known as Teratocarcinoma-
derived growth factor 1 (TDGF1), is a member of the EGF-CFC family that is required for proper laterality development in humans (1, 2). It is an obligate coreceptor involved in the NODAL ligand signaling pathway, a developmental program implicated in midline, forebrain, and left-right axis development (2). Thus, Cripto 1 could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm (1). It also increases migration of cells in vitro (3). Cripto 1 is expressed in embryonic stem (ES) cells and during the early phases of embryo development (4). Furthermore, it is expressed at high levels in the majority of different types of human carcinomas including breast, colon, and lung (5). Recommended Applications WB, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IP: 1:10 - 100 Species Reactivity * Human, Mouse *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) NCCIT and (B) F9 cell lysates using anti-Cripto 1 / 3 RabMAb (cat. #5108-1). Specificity A synthetic peptide corresponding to residues in human Cripto 1 was used as an immunogen. This antibody cross-reacts with Cripto 3. This antibody was developed as part of a collaboration between Epitomics, the National Cancer Institute's Center for Cancer Research and the lab of David Solomon. |
| 性状 | 【反应特异性】Human , Mouse
【克隆 ID】EPNCI106B 【用途】WB , IP 【抗原分子量】21kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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