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Cytokeratin 17 DyLight® 594 (KRT17)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113485-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | KRT17 antibody, K17 antibody, PC antibody, PC2 antibody, PCHC1 antibody, Keratin, type I cytoskeletal 17 antibody, Keratin-17 antibody |
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| 产品参数 | 【产品介绍】Among the members of the cytokeratin
(CK) subfamily of intermediate filament (IF) proteins, Cytokeratin 17 is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. It has an unusual expression pattern in normal and diseased states, and it has potential importance in tumor diagnosis. Cytokeratin 17 synthesis seems to be a marker of basal cell differentiation in complex epithelia, therefore it is indicative of a certain type of epithelial "stem cells" (1). It has been shown that Cytokeratin 17 regulates cell growth through binding to the adaptor protein 14-3-3 sigma. These findings reveal a new and unexpected role for the intermediate filament cytoskeleton in influencing cell growth and size by regulating protein synthesis (2). Cytokeratin 17 is expressed in the nail bed, hair follicle, sebaceous glands, and other epidermal appendages (3). Recommended Applications ICC Applications and Recommended Dilution Factors ICC: 1:200 Species Reactivity Human Products Data Immunofluorescent analysis of A431 cells using Cytokeratin 17 RabMAb (DyLight® 594 conjugate) (red) and dapi (blue). Specificity A synthetic peptide corresponding to residues on the N-terminus in human Cytokeratin 17 was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EP1623 【用途】ICC 【抗原分子量】50kDa |
| 贮存 | Storage Condition and Buffer Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt. |
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