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Cytokeratin 16 (KRT16)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113484-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | KRT16 antibody, CK16 antibody, FNEPPK antibody, K16 antibody, K1CP antibody, KRT16A antibody, NEPPK antibody, Keratin, type I cytoskeletal 16 antibody, Keratin-16 antibody |
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| 产品参数 | 【产品介绍】The human type I keratin 16 (CK16)
is constitutively expressed in a number of complex epithelial tissues, including skin, but is better known for its induction under conditions favoring enhanced proliferation or abnormal differentiation, including wound healing, psoriasis, and cancer (1). CK16 is expressed in suprabasal interfollicular epidermis in wound healing and other pathological conditions associated with hyperproliferation, such as psoriasis and are induced when keratinocytes are cultured in vitro. However, CK16 is also constitutively expressed in normal suprabasal mucosal and palmoplantar keratinocytes (2). Pachyonychia congenita (PC) is a group of inherited ectodermal dysplasias, the characteristic phenotype being hypertrophic nail dystrophy. The PC-1 phenotype may be distinguished by the absence of the epidermal cysts found in PC-2, and it has been shown to be caused by mutations in either keratin K16 or its expression partner, the K6a isoform of K6. Mutations in K16 have also been shown to cause a milder related phenotype, focal non-epidermolytic palmoplantar keratoderma (3). Recommended Applications WB, IHC, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:2000 - 10,000 IHC: 1:100 - 250 ICC: 1:100 - 250 IP: 1:10 - 100 FC: 1:10 - 100 Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on HaCat cell lysate using anti-CK-16 RabMAb (cat. # 2142-1), dilution 1:10,000. B. Immunohistochemical analysis of paraffin-embedded human squamous cervical carcinoma using anti-CK16 RabMAb (cat. #2142-1). Specificity A synthetic peptide corresponding to residues near the N-terminus of human CK-16 was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EP1615Y 【用途】WB , IHC , ICC , FC , IP 【抗原分子量】48kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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