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Cytokeratin 10 (KRT10)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113482-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | KRT10 antibody, BCIE antibody, BIE antibody, CK10 antibody, EHK antibody, K10 antibody, KPP antibody, Keratin, type I cytoskeletal 10 antibody, Keratin-10 antibody |
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| 产品参数 | 【产品介绍】Cytokeratin 10 (CK10) is a heterotetramer of
two type I and two type II keratins. CK10 is typically associated with cytokeratin 1 (CK1). CK10 is expressed in all suprabasal cell layers, and it is part of the acidic/high molecular weight keratin subfamily. Defects in CK10 cause Epidermolytic hyperkeratosis (EHK), a hereditary skin hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum (1). CK10 has also been linked to cause annular epidermolytic ichthyosis (AEI), also known as cyclic ichthyosis with epidermolytic hyperkeratosis. CK10, along with CK14, 15, 16, and 20, can be used to determine if a neoplasm originated from an epithelial or non-epithelial origin, such as the determination of metastatic malignant tumors of epithelial origin (2). Recommended Applications WB, IHC, ICC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 IHC: 1:100 - 250 ICC: 1:100 - 250 IP: 1:30 Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data A. Western blot analysis on HaCat cell lysate using anti-cytokeratin 10 RabMAb (cat. # 2210-1), dilution 1:100,000. B. Paraffin-embedded human skin tissue stained with anti-CK-10 RabMAb. Note positive staining of suprabasal layers of keratinizing stratified epithelia (cat# 2210-1). Specificity A synthetic peptide corresponding to residues in the C-term of human Cytokeratin 10 was used as immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EP1607Y 【用途】WB , IHC , ICC , IP 【抗原分子量】60kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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