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KRT4 antibody
英文名：Rabbit Monoclonal Antibody
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| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113488-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | Cytokeratin 4 (KRT4), CK4 antibody, CYK4 antibody, FLJ31692 antibody, K4 antibody, Keratin, type II cytoskeletal 4 antibody, Type-II keratin Kb4 antibody |
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| 产品参数 | 【产品介绍】Keratins are a family of structurally
related proteins that form the intermediate filament cytoskeleton in epithelial cells (1). Keratins are expressed in pairs by epithelial cells in a tissue and cell specific manner (2). The major differentiation specific keratins of the buccal mucosa, nasal, esophageal and anogenital epithelia are cytokeratin 4 and cytokeratin 13 (2). Cytokeratin 4 and cytokeratin 13 form heterodimers in normal epithelial cells (3). In humans, cytokeratin 4 is present in all layers of the epidermis at 10 weeks and gradually disappears (3). Genetic mutations in cytokeratin 4 cause white sponge nevus (WSN), an autosomal dominant disorder that affects noncornified stratified squamous epithelia (4). Recommended Applications WB, IHC, ICC Applications and Recommended Dilution Factors WB: 1: 1,000 - 10,000 IHC: 1: 100 - 250 ICC: 1: 100 - 250 Species Reactivity * Human, Rat *Mouse cross reactivity tested by western blot and IHC Rat cross reactivity tested by western blot only Products Data Western blot analysis on (A) A431 and (B) human uterus cell lysates using anti-Cytokeratin 4 RabMAb (cat. # 2843-1). Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 4 RabMAb. Note positive staining of squamous cells (cat. #2843-1). Immunofluorescent staining of A431 cells using anti- Cytokeratin 4 RabMAb (cat. #2843-1). Specificity A synthetic peptide corresponding to residues in human Cytokeratin 4 was used as an immunogen. |
| 性状 | 【反应特异性】Human , Rat
【克隆 ID】EPR1598 【用途】WB , IHC , ICC 【抗原分子量】59kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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