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| 生化科研试剂 >> 抗体产品 >> 一抗 |
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Cytokeratin 6 (KRT6A)
Rabbit Monoclonal Antibody |
| 别 名： |
KRT6A antibody, CK6A antibody, CK6C antibody, CK6D antibody, K6A antibody, K6C antibody, K6D antibody, KRT6C antibody, KRT6D antibody, Keratin, type II cytoskeletal 6A antibody, Type-II keratin Kb6 antibody |
| 货号 |
品名 |
规格 |
包装 |
单价 |
货期 |
库存 |
| 1227177692 |
Cytokeratin 6 (KRT6A) |
|
100ul |
询价 |
现货 |
3天 |
| 提示信息：偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。 |
| 性 状： |
【反应特异性】Human
【克隆 ID】EPR1603Y
【用途】WB , IHC , ICC , IP
【抗原分子量】60kDa |
| 质量标准： |
【产品介绍】The human type II Cytokeratin 6 (CK6; 56 kDa)
is expressed in a heterogeneous array of epithelial
tissues under normal conditions, but is better known for
its strong induction in stratified epithelia that feature
an enhanced cell proliferation rate or
abnormal differentiation. It has been demonstrated that
CK6 isoform, CK6a, is clearly the dominant CK6 isoform
in skin tissue samples and cultured epithelial cell
lines and that the various isoforms are
differentially regulated within and between
epithelial tissue types (1). The murine genome is known
to have two keratin 6 (CK6) genes, mouse CK6, CK6a and
MK6b. These genes display a complex expression pattern
with constitutive expression in the epithelia of
oral mucosa, hair follicles, and nail beds (2).
Pachyonychia congenital (PC) is characterized
by hypertrophic nail dystrophy and associated
ectodermal features. PC-1 subtype is associated
with mutations in keratins 6a or 16, whereas PC-2 subtype
is linked to mutations in keratins 6b or 17 (3).
Recommended Applications
WB, IHC, ICC, IP
Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:100 - 250
IP: 1:30
Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data
A. Western blot analysis on A431 lysate
using anti-Cytokeratin 6 RabMAb (cat. # 1951-1),
dilution 1:100,000 B. Immunohistochemical staining of paraffin-embedded
human squamous cervical carcinoma using
anti-Cytokeratin 6 RabMAb (cat. #1951-1). C. Immunofluorescent staining of A431 cells
using anti-Cytokeratin 6 RabMAb (cat. #1951-1). Specificity A synthetic peptide corresponding to residues on
the C-terminus of human Cytokeratin 6 was used as
an immunogen. |
| 贮 存： |
Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt. |
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