Cytokeratin 7 (N-term)

英文名:Rabbit Polyclonal Antibody
Cas号:
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别 名 KRT7 antibody, CK7 antibody, K2C7 antibody, K7 antibody, MGC129731 antibody, MGC3625 antibody, SCL antibody, Keratin, type II cytoskeletal 7 antibody, Sarcolectin antibody, Type-II keratin Kb7 antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】Keratins are cytoplasmic intermediate
filament proteins expressed by epithelial cells.
Keratin 7 (K7) is expressed in a wide range of
epithelial structures in humans. The expression pattern
in mice is similar to the reported human distribution,
with substantial expression observed in lung,
bladder, mesothelium, hair follicle, and ductal
structures (1). Protein expression levels of CK7
appear significantly higher in chromophobe RCC compared
to oncocytoma (p < 0.001). Studies provide further
evidence that CK7 and parvalbumin immunostains may be
useful in differentiating oncocytoma from chromophobe RCC
in problematic cases (2). Also, the pattern
of immunohistochemical expression of CK 7 along with CK
20 is commonly used to assess possible primary sites
of metastatic carcinomas (3).


Recommended Applications

WB, IHC, ICC, IP
Applications and Recommended Dilution Factors

WB: 1:2000
IHC: 1:100 - 250
ICC: 1:100 - 250
IP: 1:30
Species Reactivity *

Human

*Cross reactivity determined by western blot only.

Products Data

A. Western blot analysis on T-47D cell lysate of
using anti-CK-7 Rabbit Polyclonal (cat. # 1899-1),
dilution 1:2000.

B. Immunohistochemical analysis of paraffin-embedded
human bladder cancer using anti-CK-7 Rabbit Polyclonal
(cat. #1899-1).

C. Immunofluorescent staining of HeLa cells using
anti-CK7 Rabbit Polyclonal antibody (cat. #1899-1).

Specificity

A synthetic peptide corresponding to residues near
the N-terminus of human CK-7 was used as an immunogen.
性状 【反应特异性】Human
【克隆 ID】polyclonal
【用途】WB , IHC , ICC , IP
【抗原分子量】55kDa
贮存 Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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