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GCDFP-15 (PIP)
英文名：Rabbit Monoclonal Antibody
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308113621-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | PIP antibody, GCDFP-15 antibody, GCDFP15 antibody, GPIP4 antibody, Prolactin-inducible protein antibody, gp17 antibody |
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| 产品参数 | 【产品介绍】Gross cystic disease fluid protein
(GCDFP-15), also called prolactin-inducible protein (PIP), is a single polypeptide chain with a versatile function in human reproductive and immunological systems (1). It is unique because of its small size (1). GCDFP-15 binds to CD4, exerts a potent inhibition on T lymphocyte apoptosis mediated by CD4/T-cell receptor (TCR) activation, and carries a fibronectin-specific aspartyl protease activity (2). Its ability to bind with other molecules like immunoglobulin G (IgG), actin, and zinc alpha2- glycoprotein (ZAG) shows its various biological activities (1). GCDFP-15 is expressed in benign and malignant human breast tumors and in normal exocrine organs such as sweat, salivary and lacrimal glands (1). It is up regulated by prolactin and androgens, while it is down regulated by estrogen (1). Due to its expression in breast cancer, GCDFP-15 is used as a prognostic biomarker (3, 4). Recommended Applications WB, IHC, ICC Applications and Recommended Dilution Factors WB: 1 : 1,000 - 10,000 IHC: 1 : 100 - 250 ICC: 1 : 100 - 250 Species Reactivity Human Products Data Western blot analysis on (A) T47-D and (B) breast cancer cell lysates using anti-GCDFP-15 RabMAb (cat. # 2847-1). Immunohistochemical staining of paraffin-embedded human breast carcinoma tissue using anti-GCDFP-15 RabMAb (cat. #2847-1). Specificity A synthetic peptide corresponding to residues in human GCDFP-15 was used as an immunogen. |
| 性状 | 【反应特异性】Human
【克隆 ID】EPR1582 【用途】WB , IHC , ICC 【抗原分子量】17kDa |
| 贮存 | Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
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