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HNF4 Alpha DyLight® 488
英文名:HNF4A
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检测信息查询
货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
1308114411-100ul | 现货 | 0 | ¥0 | 请登录 |
别 名 | HNF4A antibody, FLJ39654 antibody, HNF4 antibody, HNF4a7 antibody, HNF4a8 antibody, HNF4a9 antibody, HNF4alpha antibody, MODY antibody, MODY1 antibody, NR2A1 antibody, NR2A21 antibody, TCF antibody, TCF14 antibody, Hepatocyte nuclear factor 4-alpha antibo |
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产品参数 | 【产品介绍】HNF4 (Hepatocyte Nuclear Factor 4) is a
nuclear receptor protein belonging to the steroid hormone receptor superfamily. HNF4 is commonly expressed in the liver and plays a critical role in liver development by establishing and maintaining hepatocyte differentiation (1). In human, two isoforms of HNF4 exists, alpha and gamma. HNF4 alpha is transcriptionally controlled transcription factor, which binds to DNA sites required for the transcription of alpha 1- antitrypsin, Apo CIII, transthyretin genes, and HNF1 alpha (2). HNF4 alpha interacts with PGC-1 to activate gluconeogenesis, leading to lipoprotein metabolism regulation (3). HNF4 alpha defects are known to cause type I diabetes (4). Recommended Applications ICC Applications and Recommended Dilution Factors ICC: 1:50 - 100 Species Reactivity Human Products Data Immunofluorescent staining of HepG2 cells using anti-HNF-4 antibody conjugated with Dylight 488 (green, Cat# 4580-1) and Dapi (blue). Specificity A synthetic peptide corresponding to residues in human HNF4 was used as an immunogen. |
性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human 【克隆 ID】EPR3648 【用途】ICC 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】52kDa |
贮存 | Store at 2-8° C. PBS (pH 7.2), 0.02% sodium azide, 0.05% BSA. Protect from light. Stable for 6 months from date of receipt. |