HP1 alpha (CBX5)

英文名:HP1 alpha (CBX5)
Cas号:
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别 名 CBX5 antibody, HP1 antibody, HP1A antibody, Chromobox protein homolog 5 antibody, Antigen p25 antibody, Heterochromatin protein 1 homolog alpha antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】HP1 alpha is a highly conserved
nonhistone protein, which is a member of the
heterochromatin protein family. It is enriched in
the heterochromatin and associated with centromeres.
HP1 alpha has a single N-terminal chromodomain that
can bind to histone proteins via methylated lysine
residues and a C-terminal chromo shadow-domain (CSD) that
is responsible for the homodimerization and interaction
with a number of chromatin-associated nonhistone
proteins. It is involved in the formation of a
functional kinetochore through interaction with
essential kinetochore proteins (1).

Recommended Applications
WB, FC
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
FC: 1:10 - 100
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) HeLa, (B) SH-SY5Y, (C)
MCF-7, (D) A431, (E) C6, (F) RAW 264.7, (G) PC-12,
and (H) NIH/3T3 cell lysates using anti-HP1 alpha
RabMAb (cat. #5346-1).

Flow cytometric analysis of permeabilized SH-SY5Y
cells using anti-HP1 alpha RabMAb (red)
(catalog # 5346-1) or a rabbit IgG (negative) (green).

Specificity
A synthetic peptide corresponding to residues in human
HP1 alpha was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR5776
【用途】WB , FC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】22kDa
贮存 Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
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