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HOXB4
英文名：HoxB4
Cas号：
Cas号：
检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114413-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | HOXB4 antibody, HOX-2.6 antibody, HOX2 antibody, HOX2F antibody, Homeobox protein Hox-B4 antibody, Homeobox protein Hox-2.6 antibody, Homeobox protein Hox-2F antibody |
| Cas号 | |
| M D L | |
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| 产品参数 | 【产品介绍】Homeobox transcription factors (Hox) are
highly conserved developmental proteins that are involved in embryonic and early hematopoietic development. Specifically, Homeobox B4 (HoxB4) is a transcription factor that is involved in the developmental regulation of specific positional identities on the anterior-posterior axis of cells. Like all members of the HOX family, HoxB4 is abundantly expressed in primitive hematopoietic stem cells (HSC), but then it declines with lineage-specific terminal differentiation (1). In HSC's, stem cell self-renewal activity is regulated by USF1/2 binding to HoxB4, where binding possibly favors stem cell self-renewal instead of cell differentiation. Jun-B and Fra-1 have been linked to key mediators during cell proliferation and differentiation induced by HoxB4, which leads to an increase in expression of Cyclin D1 and G1 shortening (2). Recommended Applications WB, ICC, IP Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 ICC: 1:100 - 250 IP: 1:10 - 100 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) K562, (B) Jurkat, (C) RAW 264.7, and (D) PC-12 cell lysates using anti-HoxB4 RabMAb (cat. #5110-1). Immunofluorescent staining of NCCIT cells using anti-HoxB4 RabMAb (cat. #5110-1). Specificity A synthetic peptide corresponding to residues in human HoxB4 was used as an immunogen. |
| 性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR1917 【用途】WB , ICC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】34kDa |
| 贮存 | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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