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hnRNP C2
英文名：HNRNPC
Cas号：
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114412-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | HNRNPC antibody, C1 antibody, C2 antibody, HNRNP antibody, HNRPC antibody, MGC104306 antibody, MGC105117 antibody, MGC117353 antibody, MGC131677 antibody, SNRPC antibody, Heterogeneous nuclear ribonucleoproteins C1/C2 antibody, antibody |
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| 产品参数 | 【产品介绍】Heterogeneous nuclear
ribonucleoproteins (hnRNPs) are predominantly nuclear RNA-binding proteins that form complexes with RNA polymerase II transcripts. These proteins function in a variety of cellular activities, ranging from transcription and pre-mRNA processing in the nucleus to cytoplasmic mRNA translation and turnover (1). hnRNP C2 is one of the most abundant proteins in the nucleus, and shown to have roles in cellular differentiation and proliferation (2). A novel nuclear export is activated by the ROCK signaling pathway to exclude hnRNP C2 from the nucleus, by which the compartmentalization of specific hnRNP components is disturbed in apoptotic cells (3). Overexpression of hnRNP C2 in hepatocellular carcinoma (HCC) tissues has been reported in 70 HCC samples, suggesting its potential as a protein tumor marker (4). Recommended Applications WB, IHC, ICC, IP, FC Applications and Recommended Dilution Factors WB: 1:10,000 - 50,000 IHC: 1:250 - 500 ICC: 1:250 - 500 IP: 1:10 - 100 FC: 1:10 - 100 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) HeLa, (B) MCF-7, (C) HepG2, (D) K562, and (E) 293T cell lysates using anti-hnRNP C2 RabMAb (cat. #5449-1). Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-hnRNP C2 RabMAb (cat. #5449-1). Immunohistochemical analysis of paraffin-embedded human thyroid carcinoma tissue using anti-hnRNP C2 RabMAb (cat. #5449-1). Specificity A synthetic peptide corresponding to residues in human hnRNP C2 was used as an immunogen. This antibody is specific to isoform C2. This antibody was developed as part of a collaboration between Epitomics, the National Cancer Institute's Center for Cancer Research and the lab of Mirit Aladjem. |
| 性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat 【克隆 ID】EPNCIR152 【用途】WB , IHC , ICC , FC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】42kDa |
| 贮存 | Store at -20° C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. |
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