1. 首页
  2. 生化科研试剂
  3. 抗体产品
  4. 一抗

IDE

英文名：IDE
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308114428-100ul 现货 0 ￥0 请登录
- +
偏远地区如新疆西藏宁夏甘肃等地可能无法运送液体，下单前请联系客服。
别 名 IDE antibody, FLJ35968 antibody, INSULYSIN antibody, Insulin-degrading enzyme antibody, Insulysin antibody
Cas号
M D L
分子式
分子量
产品参数 【产品介绍】IDE is a zinc metallopeptidase that
degrades intracellular insulin, and thereby
terminates insulin's activity, as well as participating
in intercellular peptide signaling by degrading
diverse peptides such as glucagon, amylin, bradykinin,
and kallidin. The preferential affinity of this enzyme
for insulin results in insulin-mediated inhibition of
the degradation of other peptides such as beta-
amyloid. Deficiencies in IDE's function are associated
with Alzheimer's disease and type 2 diabetes mellitus,
but mutations in IDE have not been shown to be causative
for these diseases. It localizes primarily in the
cytoplasm, but in some cell types it localizes to
the extracellular space, cell membrane, peroxisome,
and mitochondrion (1).

Recommended Applications
WB, IHC
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:50 - 100
Species Reactivity *
Human, Mouse, Rat
*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on (A) HeLa, (B) HepG2, (C) A375,
and (D) K562 cell lysates using anti-IDE RabMAb
(cat. #5282-1).

Immunohistochemical analysis of paraffin-embedded
human colon tissue using anti-IDE RabMAb (cat. #5282-1).

Specificity
A synthetic peptide corresponding to residues in human
IDE was used as an immunogen.
性状 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6098(2)
【用途】WB , IHC
【产品性状】
【阳性对照】
【产品浓度】
【细胞定位】
【抗原分子量】120kDa
贮存 Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的，不可用于人类或动物的临床诊断或者治疗，非药用，非食用。
X
QQ