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IFN alpha R1
英文名：IFNAR1
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114431-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | IFNAR1 antibody, AVP antibody, IFN-alpha-REC antibody, IFNAR antibody, IFNBR antibody, IFRC antibody, Interferon alpha/beta receptor 1 antibody, Type I interferon receptor 1 antibody |
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| 产品参数 | 【产品介绍】Interferon alpha receptor 1 (IFN alpha R1) is
a class II cytokine receptor that belongs to the type I human interferons (IFNs) family. IFNs plays a role in antiviral, antiproliferative, immunomodulatory, antitumor, and antiparasitic activities by inducing transcription of IFN-stimuated genes (ISGs) through activation of the Jak-STAT pathway. Specifically, IFN alpha R1 is a 135-kDa signal transducing subunit of the IFN alpha/beta receptor complex (IFN-α R) (1). IFN alpha R1 is phosphorylated through PTK- and PKC- mediated phosphorylation, which initiates docking of STAT proteins to IFNs. This leads to activation of STAT proteins by PTK-mediated phosphorylation. The mechanism behind the amplification of IFN alpha R complex mediated transmembrane signaling has been linked to tyrosine phosphorylation on IFN alpha R1 (2). Recommended Applications WB Applications and Recommended Dilution Factors WB: 1:1,000 - 10,000 Species Reactivity * Human, Mouse, Rat *Species cross-reactivity is based on WB analysis. Products Data Western blot analysis on (A) HeLa, (B) HeLa treated with IFN-alpha, (C) K562, and (D) U937 cell lysates using anti-IFN alpha R1 RabMAb (cat. #5330-1). Specificity A synthetic peptide corresponding to residues in human IFN alpha R1 was used as an immunogen. |
| 性状 | 【产品类型】Rabbit Monoclonal Antibody
【反应特异性】Human , Mouse , Rat 【克隆 ID】EPR6244 【用途】WB 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】90-130kDa |
| 贮存 | Store at -20 °C. Antibody buffer, 0.01% sodium azide, 50% Glycerol and 0.05% BSA. Stable for 12 months from date of receipt |
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