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LAT Rabbit Antibody
英文名：LAT Rabbit Antibody
Cas号：
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检测信息查询
| 货号 | 规格 | 货期 | 库存 | 价格 | 会员价 | 订购 |
| 1308114487-100ul | 现货 | 0 | ￥0 | 请登录 |
| 别 名 | LAT antibody, LAT1 antibody, pp36 antibody, Linker for activation of T-cells family member 1 antibody, p36-38 antibody |
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| 产品参数 | 【产品介绍】LAT (linker f o r activation of T-cells)
is involved in the T-cell antigen recept o r (TCR) signal transduction pathway, a n d may play an imp o r tant role downstream in activating protein tyrosine kinases (1). LAT is phosph o r ylated by ZAP-70/Syk protein tyrosine kinases leading to recruitment of multiple signaling molecules (2). It has been found that Tyr191 a n d Tyr171 are required f o r T-cell activation a n d Tyr132 is required f o r the activation of PLCgamma1 a n d Ras signaling pathways, respectively. Tyr226 a n d Tyr191 are required f o r Vav binding, whereas Tyr171 a n d Tyr132 are necessary f o r association a n d activation of phosphoinositide 3-kinase activity a n d PLCgamma1 (3). WB: 1:500 IHC: 1:100 Flow Cytometry: 1:40 IP: 1:60 A. Western blot analysis on Jurkat cell lysate using anti-LAT RabMAb (catalog #1499-1), dilution 1:500. B. Immunohistochemical analysis of paraffin-embedded human lymph node using anti-LAT RabMAb (catalog #1499-1). |
| 性状 | 【产品类型】Rabbit Monoclonal IgG
【反应特异性】 【克隆 ID】Y109 【用途】WB , IHC , FC , IP 【产品性状】 【阳性对照】 【产品浓度】 【细胞定位】 【抗原分子量】36/38 kDa |
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