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帕妥珠单抗
英文名:Pertuzumab
Cas号:380610-27-5
Cas号:380610-27-5
检测信息查询
别 名 | 帕妥株单抗;帕妥珠单抗 |
Cas号 | 380610-27-5 |
M D L | |
分子式 | C17H27NO2 |
分子量 | 277.40178 |
产品参数 | Description
Pertuzumab, a humanized monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer. IC50 & Target EGFR[1] Storage Please store the product under the recommended conditions in the Certificate of Analysis. References [1]. Nahta R, et al. The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survivalof breast cancer cells. Cancer Res. 2004 Apr 1;64(7):2343-6. [2]. Scheuer W, et al. Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor models. Cancer Res. 2009 Dec 15;69(24):9330-6. |
性状 | Pertuzumab 是一种人源化单克隆抗体,是一种HER2二聚抑制剂。可用于治疗转移性HER2 阳性乳腺癌。 |
贮存 |