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阿维鲁单抗
英文名：Avelumab
Cas号：1537032-82-8
Cas号：1537032-82-8
检测信息查询
| 别 名 | |
| Cas号 | 1537032-82-8 |
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| 产品参数 | Description
Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity. IC50 & Target PD-1/PD-L1[1] References [1]. Fujii R, et al. Enhanced killing of chordoma cells by antibody-dependent cell-mediated cytotoxicity employing the novel anti-PD-L1 antibody avelumab. Oncotarget. 2016 Jun 7;7(23):33498-511. [2]. Grenga I, et al. A fully human IgG1 anti-PD-L1 MAb in an in vitro assay enhances antigen-specific T-cell responses. Clin Transl Immunology. 2016 May 20;5(5):e83. [3]. Vandeveer AJ, et al. Systemic Immunotherapy of Non-Muscle Invasive Mouse Bladder Cancer with Avelumab, an Anti-PD-L1 Immune Checkpoint Inhibitor. Cancer Immunol Res. 2016 May;4(5):452-62. |
| 性状 | Avelumab 是一个人 IgG1 抗 PD-L1 单克隆抗体，具有潜在的抗体依赖性细胞介导的细胞毒性作用。 |
| 贮存 | Storage Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month |
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