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Recombinant Human Interleukin-22
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| 性状 | Recombinant Human Interleukin-22 来源于 E. coli，是一种参与免疫应答的细胞因子。
Synonyms rHuIL-22; Cytokine Zcyto 18; IL-TIF Species Human Source E. coli Accession Q9GZX6 Gene ID 50616 Molecular Weight Approximately 16.9 kDa AA Sequence MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI Biological Activity The ED50 is <1 ng/mL as measured by COLO 205 (human colon carcinoma cells). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Interleukin-22 (rHuIL-22) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human Interleukin-22 (rHuIL-22) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Interleukin-22 (IL-10-related T cell-derived inducible factor/IL-TIF/IL-22) is a novel cytokine belonging to the IL-10 family. Recombinant humanIL-22 (hIL-22) is found to activate the signal transducers and activators of transcription factors 1 and 3 as well as acute phase reactants in several hepatoma cell lines, suggesting its involvement in the inflammatory response. IL-22 is a member of interleukin-10 family of cytokines, which also includes IL-19, IL-20, and IL-24 in addition to IL-10 and a number of its viral homologs[1]. |
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