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Recombinant Rat Interferon-gamma

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132619-10 μg 0 ￥1540 请登录
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1308132619-50 μg 0 ￥2800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Rat Interferon-gamma 是一种促炎性细胞因子，具有高效的免疫调节功能，同时可抗细胞增殖，抗病毒等。】
Synonyms
rRtIFN-γ; IFNG; IFN-gamma; Interferon gamma ; 重组大鼠干扰素-γ
Species
Rat

Source
E. coli

Accession
P01581

Gene ID
25712

Molecular Weight
Approximately 15.5 kDa

AA Sequence
GTLIESLESL KNYFNSSSMD AMEGKSLLLD IWRNWQKDGN TKILESQIIS FYLRLFEVLK DNQAISNNIS VIESHLITNF FSNSKAKKDA FMSIAKFEVN NPQIQHKAVN ELIRVIHQLS PESSLRKRKR SRC

Biological Activity
The ED50 is <0.5 ng/mL as measured by WEHI-279 cells, corresponding to a specific activity of >2 × 106 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Rat Interferon-gamma (rRtIFN-γ) to 100 µg/mL using ddH2O or diluted with PBS.

Storage & Stability
Lyophilized recombinant Rat Interferon-gamma (rRtIFN-γ) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Interferon-gamma (IFN-γ) is a cytokine with potent immunomodulatory, anti-proliferative, and antiviral properties. IFN-γ activates cells via a different receptor than IFN-α and IFN-β, which accounts for the different physiological properties of the proteins. Production of IFN-γ is largely restricted to activated CD4+ TH1 T cells, CD8+ T cells, and natural killer cells. One of the most important consequences of IFN-γ secretion is the activation of macrophages. In addition, IFN-γ plays a central role in inflammatory responses by activating endothelial cells, promoting TH1 cell development and cellular immune responses, and up-regulation of major histocompatability complex protein expression on antigen-presenting cells[1].
贮存
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