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Recombinant Rat Interleukin-1 beta

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132621-10 μg 0 ￥3800 请登录
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1308132621-50 μg 0 ￥10400 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Rat Interleukin-1 beta 是一种免疫调节细胞因子，可介导广泛的免疫反应。
Synonyms
rRtIL-1β; Catabolin; IL1F2; IL-1 beta; IL1B
Species
Rat

Source
E. coli

Accession
Q5BKB0

Gene ID
24494

Molecular Weight
Approximately 17.3 kDa

AA Sequence
VPIRQLHCRL RDEQQKCLVL SDPCELKALH LNGQNISQQV VFSMSFVQGE TSNDKIPVAL GLKGLNLYLS CVMKDGTPTL QLESVDPKQY PKKKMEKRFV FNKIEVKTKV EFESAQFPNW YISTSQAEHR PVFLGNSNGR DIVDFTMEPV SS

Biological Activity
The ED50 is <10 pg/mL as measured by mouse D10S cells, corresponding to a specific activity of >1.0 × 108 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Rat Interleukin-1 beta (rRtIL-1β) to 100 µg/mL using ddH2O.

Storage & Stability
Lyophilized recombinant Rat Interleukin-1 beta (rRtIL-1β) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Interleukin-1 beta (IL-1β) is a proinflammatory cytokine, produced in response to inflammatory agents by a variety of cells, including, monocytes, macrophages, and dendritic cells (DCs). Recombinant rat IL-1β and IL-6 synergistically enhance C3 mRNA levels and complement component C3 secretion by H-35 rat hepatoma cells. In rat hepatoma H-35 cells, recombinant rat IL-1β, IL-6, and IFN-γ increase the quantity of C3 mRNA and secreted C3 protein, an observation consistent with reports that C3 is an acute phase protein in the rat[1].
贮存
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