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Recombinant Human Fibroblast Growth Factor 18
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| 性状 | Recombinant Human Fibroblast Growth Factor 18 是一种肝素结合多肽生长因子，在软骨的生长、成熟，以及功能性软骨和骨组织的发育过程中起作用。
Synonyms rHuFGF-18; zFGF5; FGF18 ; 重组人源成纤维细胞生长因子 18 Species Human Source E. coli Accession O76093 Gene ID 8817 Molecular Weight Approximately 20.3 kDa AA Sequence MAEENVDFRI HVENQTRARD DVSRKQLRLY QLYSRTSGKH IQVLGRRISA RGEDGDKYAQ LLVETDTFGS QVRIKGKETE FYLCMNRKGK LVGKPDGTSK ECVFIEKVLE NNYTALMSAK YSGWYVGFTK KGRPRKGPKT RENQQDVHFM KRYPKGQPEL QKPFKYTTVT KRSR Biological Activity The ED50 is <10 ng/mL as measured by 3T3 cells, corresponding to a specific activity of > 1.0 × 105 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor 18 (rHuFGF-18) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Fibroblast Growth Factor 18 (rHuFGF-18) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Fibroblast growth factor 18 (FGF18), a secreted heparin-binding polypeptide growth factor, is related to FGF8 and 175 and has been shown to have a number of functions in different organs. FGF18 is involved in cartilage growth and maturation and is implicated in the development of functional cartilage and bone tissue. It is also involved in processes within mature cartilage10-13 as well as being shown to have a role in enhancing regeneration and repair[1]. Fibroblast growth factor 18 (FGF18) acts as an important role in skeletal growth and limb development, potentially through the modulation of osteoblasts, chondrocytes, and osteoclasts[2]. |
| 贮存 |
- Recombinant Human Transforming Growth Factor β1
- Recombinant Human Transforming Growth Factor β2
- Recombinant Human Transforming Growth Factor beta3 (HEK293-expressed)
- Recombinant Human Hepatocyte Growth Factor (CHO-expressed)
- Recombinant Human Fibroblast Growth Factor 18
- Recombinant Rat Fibroblast Growth Factor 18
- Recombinant Human 4-1BBR/TNFRSF9
- Recombinant Human Adiponectin
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