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Recombinant Human Fractalkine/CX3CL1

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132698-10 μg 0 ￥3500 请登录
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1308132698-50 μg 0 ￥9200 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human Fractalkine CX3CL1 被发现和炎症疾病有关，比如类风湿性关节炎、类风湿性脉管炎。、
Synonyms
rHuFractalkine/CX3CL1; Neurotactin; SCYD1; NTT ; 重组人趋化因子分型素
Species
Human

Source
E. coli

Accession
P78423

Gene ID
6376

Molecular Weight
Approximately 8.6 kDa

AA Sequence
QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG

Biological Activity
Full biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 5.0-10 ng/ml.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 50 mM NaCl.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human Fractalkine/CX3CL1 (rHuFractalkine/CX3CL1) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA.

Storage & Stability
Lyophilized recombinant Human Fractalkine/CX3CL1 (rHuFractalkine/CX3CL1) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Fractalkine/CX3CL1 exists in two forms: as a membrane-anchored or as a shed 80-95K glycoprotein. Fractalkine/CX3CL1 is expressed in monocytes during inflammatory conditions. Fractalkine/CX3CL1 is also expressed in macrophages, fibroblasts, endothelial, and dendritic cells in rheumatoid arthritis (RA) synovial tissue. CX3CL1 is associated with the development of different diseases such as rheumatoid arthritis (RA), rheumatoid vasculitis (RV), Sjögren’s syndrome (SS), systemic lupus erythematosus (SLE), scleroderma, multiple sclerosis, and atherosclerosis[1].
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