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Recombinant Rhesus Macaque Granulocyte Macrophage Colony Stimulating Factor

英文名：
Cas号：
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货号 规格 货期 库存 价格 会员价 订购
1308132702-10 μg 0 ￥4200 请登录
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1308132702-50 μg 0 ￥8200 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Rhesus Macaque Granulocyte Macrophage Colony Stimulating Factor 是一种细胞因子，作用多种类型的细胞，尤其是巨噬细胞和嗜酸性粒细胞。
Synonyms
rRhGM-CSF; CSF2; Colony stimulating factor 2 ; 重组恒河猴粒细胞巨噬细胞集落刺激因子
Species
Rhesus Macaque

Source
E. coli

Accession
Q9GL44

Gene ID
574371

Molecular Weight
Approximately 14.4 kDa

AA Sequence
APARSPSPGT QPWEHVNAIQ EARRLLNLSR DTAAEMNKTV EVVSEMFDLQ EPSCLQTRLE LYKQGLQGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQI ITFQSFKENL KDFLLVIPFD CWEPVQE

Biological Activity
The ED50 is <0.1 ng/mL as measured by human TF-1 cells, corresponding to a specific activity of >1.0 × 107 units/mg.

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS, pH 7.4.

Endotoxin Level
<1 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Rhesus Macaque Granulocyte Macrophage Colony Stimulating Factor (rRhGM-CSF) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA.

Storage & Stability
Lyophilized recombinant Rhesus Macaque Granulocyte Macrophage Colony Stimulating Factor (rRhGM-CSF) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is a monomeric glycoprotein that functions as a cytokine —it is a white blood cell growth factor[1]. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Monocytes exit the circulation and migrate into tissue, whereupon they mature into macrophages and dendritic cells. GM-CSF also has some effects on mature cells of the immune system. These include, for example, inhibiting neutrophil migration and causing an alteration of the receptors expressed on the cells surface[2]. GM-CSF also plays a role in embryonic development by functioning as an embryokine produced by reproductive tract[3].
贮存
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