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Recombinant Human GRO alpha/CXCL1

英文名：
Cas号：
检测信息查询
货号 规格 货期 库存 价格 会员价 订购
1308132705-10 μg 0 ￥3800 请登录
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1308132705-50 μg 0 ￥9800 请登录
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别 名
Cas号
M D L
分子式
分子量
产品参数
性状 Recombinant Human GRO alpha/CXCL1在炎症、血管生成、肿瘤发生和伤口愈合中起重要作用。
Synonyms
rHuGRO-α/CXCL1; NAP-3; MGSA; Growth-regulated alpha protein ; 重组人 CXC 趋化因子1
Species
Human

Source
E. coli

Accession
P09341

Gene ID
2919

Molecular Weight
Approximately 7.8 kDa

AA Sequence
ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN

Biological Activity
The ED50 is <100 ng/mL as measured by CHO-K1/Gα15/hCXCR2 cells (human Gα15 and human CXCR2 stably expressed in CHO-K1 cells).

Appearance
Lyophilized powder.

Formulation
Lyophilized after extensive dialysis against PBS.

Endotoxin Level
<0.2 EU/μg, determined by LAL method.

Reconstitution
Reconstitute the lyophilized recombinant Human GRO alpha/CXCL1 (rHuGRO-α/CXCL1) to 100 μg/mL using ddH2O or PBS.

Storage & Stability
Lyophilized recombinant Human GRO alpha/CXCL1 (rHuGRO-α/CXCL1) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping
Room temperature in continental US; may vary elsewhere.

Background
CXCL1 plays a major role in inflammation, angiogenesis, tumorigenesis, and wound healing[1]. CXCL1 is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis[2]. CXCL1 has neutrophil chemoattractant activity[3]. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, arteriogenesis, inflammation, wound healing, and tumorigenesis[4].
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